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John Collis's avatar

Just a thought.

The paper referred to Simonis et al 2025 refers to G-quadruplexes, which were mentioned in the questionable paper by Seneff et al 2022, known to be against the mRNA vaccines, suggesting that the innate immune system could be suppressed because of these structures.

Is it possible that the anti vaccination movement think that Simonis et al 2025 somehow confirms the hypothesis in Seneff et al 2022?

Seneff, S., Nigh, G., Kyriakopoulos, A.M. and McCullough, P.A., 2022. Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs. Food and Chemical Toxicology, 164, p.113008.

Simonis A, Theobald SJ, Koch AE, Mummadavarapu R, Mudler JM, Pouikli A, Göbel U, Acton R, Winter S, Albus A, Holzmann D, Albert MC, Hallek M, Walczak H, Ulas T, Koch M, Tessarz P, Hänsel-Hertsch R, Rybniker J. Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages. Mol Syst Biol. 2025 Apr;21(4):341-360

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Apr 30
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John Collis's avatar

You do know that IgG4 is neutralising the same as IgG1?

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Simbolts's avatar

Efficacy ~1%

Excess Mortality since 2021 📈

Aggressive cancers since 2021 📈

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Greg Arnett, PharmD's avatar

Thank you for this. Very informative, you are correct that communication in science to others is challenging ( but necessary)…

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Dale's avatar

Also categorically false: that there is anything to vaccinate for. Categorically NOT false: excess mortality was greater AFTER than before vaccine rollout.

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